PEG-bis-amine (MW 1000)

PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560) . Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR) .

Product Specifications

CAS Number

[24991-53-5]

Product Name Alternative

Poly (ethylene glycol) -bis-amine (MW 1000)

UNSPSC

12352200

Hazard Statement

H302-H315-H319-H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/peg-bis-amine-mw-1000.html

Solubility

10 mM in DMSO

Smiles

NCCOCCOCCN.[n]

Molecular Formula

(C2H4O) nC4H12N2O

Molecular Weight

1000 (Average)

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Han X, et al. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. Int J Pharm. 2009 May 8;372 (1-2) :125-31.