ONO-RS-347
ONO-RS-347 is an orally active and potent antagonist of leukotriene C4 and D4. ONO-RS-347 inhibits LTD4-induced bronchoconstriction in guinea pigs. ONO-RS-347 is promising for research of allergic asthma and other immediate hypersensitivty diseases[1].
Product Specifications
CAS Number
103176-67-6
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ono-rs-347.html
Smiles
O=C(C1=CC=C(C=C1)OCCCCC2=CC=CC=C2)NC3=C4OC(C5=NN=NN5)COC4=CC=C3
Molecular Formula
C26H25N5O4
Molecular Weight
471.51
References & Citations
[1]Nakai H, et al. New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships. J Med Chem. 1988 Jan;31 (1) :84-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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