ATXN7L3 Polyclonal Antibody
Product Specifications
Background
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Abbreviation
ATXN7L3
UniProt
Q14CW9
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human ATXN7L3
Target
AT7L3; Ataxin 7 like 3; Ataxin 7 like protein 3; Ataxin-7-like protein 3; atxn7l3; SAGA associated factor 11 homolog; SAGA-associated factor 11 homolog
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
1.2 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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