Aposcopolamine

Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease[1].

Product Specifications

CAS Number

[535-26-2]

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

Adrenergic Receptor; Cholinesterase (ChE)

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aposcopolamine.html

Purity

98.44

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CN1[C@@](C2)([H])[C@]3([H])[C@@]([C@]1([H])C[C@@H]2OC(C(C4=CC=CC=C4)=C)=O)([H])O3

Molecular Formula

C17H19NO3

Molecular Weight

285.34

Precautions

P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P405-P501

References & Citations

[1]Yi P, et al. Integrated meta-analysis, network pharmacology, and molecular docking to investigate the efficacy and potential pharmacological mechanism of Kai-Xin-San on Alzheimer's disease. Pharm Biol. 2020 Dec;58 (1) :932-943.