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SATB1 rabbit pAb

This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016],

Product Specifications

Background

This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016]

Synonyms

DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)

Gene ID

6304

UniProt

Q01826

Cellular Locus

Nucleus matrix. Nucleus, PML body. Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences (PubMed:12692553). When sumoylated, localized in promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:18408014)..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human SATB1 AA range: 343-393

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000

Molecular Weight

85kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13194-1.pdf

Observed Molecular Weight

85 kD

Subcellular Location

Nucleus matrix . Nucleus, PML body . Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences (PubMed:12692553) . When sumoylated, localized in promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:18408014) . .

Other Product Names

DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)

Gene ID (Human)

6304

SwissProt (Human)

Q01826

Available Sizes

Curated Selection

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