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Imazodan

Imazodan is a selective inhibitor for phosphodiesterase III (PDE III), which increases myocardial contractility by blocking the cAMP degradation, and improves the contractile function of heart. Imazodan serves also as a peripheral vasodilator[1].

Product Specifications

CAS Number

[84243-58-3]

Product Name Alternative

CI 914 (free base)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/imazodan.html

Purity

99.38

Solubility

DMSO : 28.57 mg/mL (ultrasonic; adjust pH to 7 with 1 M HCl)

Smiles

O=C1CCC(C2=CC=C(N3C=CN=C3)C=C2)=NN1

Molecular Formula

C13H12N4O

Molecular Weight

240.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Goldberg AD, et al., Effectiveness of imazodan for treatment of chronic congestive heart failure. The Imazodan Research Group. Am J Cardiol. 1991 Sep 1;68 (6) :631-6.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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