Imazodan
Imazodan is a selective inhibitor for phosphodiesterase III (PDE III), which increases myocardial contractility by blocking the cAMP degradation, and improves the contractile function of heart. Imazodan serves also as a peripheral vasodilator[1].
Product Specifications
CAS Number
84243-58-3
Product Name Alternative
CI 914 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/imazodan.html
Purity
99.38
Solubility
DMSO : 28.57 mg/mL (ultrasonic; adjust pH to 7 with 1 M HCl)
Smiles
O=C1CCC(C2=CC=C(N3C=CN=C3)C=C2)=NN1
Molecular Formula
C13H12N4O
Molecular Weight
240.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Goldberg AD, et al., Effectiveness of imazodan for treatment of chronic congestive heart failure. The Imazodan Research Group. Am J Cardiol. 1991 Sep 1;68 (6) :631-6.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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