BNP (1-21), Pro (Human)

BNP (1-21), Pro (Human) is a peptide containg 21 amino acids. B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone. BNP together with the highly homologous atrial natriuretic peptide, it forms a dual natriuretic peptide system of the heart. BNP is responsible for changes in the heart organogenesis and is associated with transition to extrauterine life[1][2][3].

Product Specifications

CAS Number

[286373-49-7]

UNSPSC

12352209

Target

Natriuretic Peptide Receptor (NPR)

Type

Peptides

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bnp-1-21-pro-human.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(NCC(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)NC(CNC([C@H](CC(C)C)NC([C@H]2N(CCC2)C([C@@H](N)CC3=CN=CN3)=O)=O)=O)=O

Molecular Formula

C89H144N28O35

Molecular Weight

2166.26

References & Citations

[1]Goetze JP, et al. Apelin: a new plasma marker of cardiopulmonary disease. Regul Pept. 2006 Jan 15;133 (1-3) :134-8.|[2]Hall C. NT-ProBNP: the mechanism behind the marker. J Card Fail. 2005 Jun;11 (5 Suppl) :S81-3.|[3]Salas GL, et al. B-type natriuretic peptide: Usefulness in the management of critically-ill neonates. Arch Argent Pediatr. 2017 Oct 1;115 (5) :483-489.