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LVGRQLEEFL (mouse) (TFA)

LVGRQLEEFL (mouse) TFA can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ) }. LVGRQLEEFL (mouse) TFA exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) TFA can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death[1][2].

Product Specifications

UNSPSC

12352209

Target

Amino Acid Derivatives; Apolipoprotein

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lvgrqleefl-mouse-tfa.html

Purity

98.20

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](N)CC(C)C)N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC1=CC=CC=C1)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)=O)C(C)C.OC(C(F)(F)F)=O.[x]

Molecular Formula

C55H90N14O16.xC2HF3O2

Molecular Weight

1203.39 (free acid)

References & Citations

[1]Su F, et al. A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. Int J Mol Sci. 2019 Sep 27;20 (19) :4807. |[2]Mishra VK, et al. Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G (*) apolipoprotein J peptide using solution NMR. Biochim Biophys Acta. 2011 Jan;1808 (1) :498-507.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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