Casein kinase 1δ-IN-5
Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM. Casein kinase 1δ-IN-5 shows neuroprotective and anti-inflammatory properties both in vitro. Casein kinase 1δ-IN-5 has the potential for neurodegenerative diseases research.
Product Specifications
CAS Number
1579991-10-8
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/casein-kinase-1δ-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(CC1=CC=CC=C1)NC2=NC3=C(S2)C=C(C(F)(F)F)C=C3
Molecular Formula
C16H11F3N2OS
Molecular Weight
336.33
References & Citations
[1]José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1
Available Sizes
Frequently Asked Questions
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