16,16-Dimethylprostaglandin F2α

16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor[1][2].

Product Specifications

CAS Number

[39746-23-1]

Product Name Alternative

16,16-Dimethyl-PGF2α

UNSPSC

12352211

Hazard Statement

H302-H360

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/16-16-dimethylprostaglandin-f2α.html

Solubility

10 mM in DMSO

Smiles

CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H]([C@H](C[C@H]1O)O)C/C=C\CCCC(O)=O

Molecular Formula

C22H38O5

Molecular Weight

382.53

Precautions

P264-P270-P280-P330-P405-P501

References & Citations

[1]Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100 (2) :172-81.|[2]Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38 (14) :2375-81.