7-Ethoxyrosmanol

7-Ethoxyrosmanol is a phenolic diterpene that is isolated from Salvia chamelaeagnea. 7-Ethoxyrosmanol has antioxidant activity in vitro and antitumor effects on neuroblastoma cells. 7-Ethoxyrosmanol alleviates hyperglycemia-induced endothelial cell dysfunction via regulating FBXL7[1][2][3].

Product Specifications

CAS Number

[111200-01-2]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7-ethoxyrosmanol.html

Solubility

10 mM in DMSO

Smiles

O=C1O[C@]2([H])[C@@H](OCC)C3=C(C(O)=C(O)C(C(C)C)=C3)[C@@]41CCCC(C)(C)[C@]24[H]

Molecular Formula

C22H30O5

Molecular Weight

374.47

References & Citations

[1]Tabata K, et, al. Phenolic diterpenes derived from Hyptis incana induce apoptosis and G (2) /M arrest of neuroblastoma cells. Anticancer Res. 2012 Nov; 32 (11) : 4781-9.|[2]Etsassala NGER, et, al. Investigation of In-Vitro Antioxidant and Electrochemical Activities of Isolated Compounds from Salvia chamelaeagnea P.J.Bergius Extract. Antioxidants (Basel) . 2019 Apr 12; 8 (4) : 98.|[3]Ni J, et al. 7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression. J Bioenerg Biomembr. 2021 Oct;53 (5) :553-560.