Penicillin G
Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection. Penicillin G has potent activity against all Gram-positive bacteria and Gram-negative cocci[1][2].
Product Specifications
CAS Number
[61-33-6]
Product Name Alternative
Benzylpenicillin
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/penicillin-g.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(CC3=CC=CC=C3)=O)N1C2=O)O
Molecular Formula
C16H18N2O4S
Molecular Weight
334.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Li D, et al. Determination of penicillin G and its degradation products in a penicillin production wastewater treatment plant and the receiving river. Water Res. 2008 Jan;42 (1-2) :307-17.|[2]Lehtinen J, et al. Promethazine renders Escherichia coli susceptible to penicillin G: real-time measurement of bacterial susceptibility by fluoro-luminometry. Int J Antimicrob Agents. 2007 Jul;30 (1) :44-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
BMC Cancer. 2023 Mar 14;23 (1) :241.|BMC Complement Med Ther. 2023 Jul 1;23 (1) :218.|Cancer Res. 2023 Apr 4;83 (7) :1048-1061.|Cancers (Basel) . 2022 Sep 28;14 (19) :4740.|Int Immunopharmacol. 2024 Feb 15:128:111524.|Oncol Lett. 2025 Jun 10;30 (2) :387.|Adv Sci (Weinh) . 2025 Jul 17:e03098.|Anal Bioanal Chem. 2025 Jan;417 (3) :615-625.|Eur J Med Chem. 2024 Dec 5:279:116842.|Eur Rev Med Pharmaco. 2019 Sep;23 (17) :7419-7429.|J Control Release. 2024 Oct 26:S0168-3659 (24) 00725-9.|Microbiol Spectr. 2025 Oct 15:e0122125.|NPJ Biofilms Microbiomes. 2024 Oct 28;10 (1) :111.|Phytomedicine. 2025 Dec:149:157553.|Water. 2025 Jun 6.|Appl Microbiol Biotechnol. 2022 Apr;106 (7) :2689-2702.|Chemosphere. 2019 Jun:225:378-387.|EBioMedicine. 2022 Apr;78:103943.|Front Physiol. 2020; 11: 605982.|Genes Dis. 2025 Apr 09.|In Vitro Cell Dev Biol Anim. 2024 Oct;60 (9) :1046-1057.|J Neuroinflammation. 2025 Aug 26;22 (1) :207.|Theranostics. 2022 Jan 1;12 (3) :1187-1203.
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