Cafestol (Standard)
Product Specifications
UNSPSC Description
Cafestol (Standard) is the analytical standard of Cafestol. This product is intended for research and analytical applications. Cafestol is an orally active diterpenoid and an inhibitor of ERK2. Cafestol has elevated blood lipids, anti-inflammatory, anti-angiogenic and anti-diabetic activities. In addition, Cafestol induces tumor cell apoptosis and autophagy, which can be used in the study of cancer[1].
Target Antigen
AP-1; Apoptosis; Autophagy; COX; ERK; FAK; NF-κB; PGE synthase
Type
Reference Standards
Related Pathways
Apoptosis;Autophagy;Immunology/Inflammation;MAPK/ERK Pathway;NF-κB;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Field of Research
Cancer; Endocrinology; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cafestol-standard.html
Smiles
C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C5=C(OC=C5)CC2)C[C@@]([C@](CO)(O)C4)([H])CC3
Molecular Weight
316.43
References & Citations
[1]Shen T, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6257R/Cafestol-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6257R/
CAS Number
469-83-0
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