11-epi-Chaetomugilin I

11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum. 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the murine L1210 leukemia cell line, and the human KB epidermoid carcinoma cell line[1].

Product Specifications

CAS Number

[1319729-88-8]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/11-epi-chaetomugilin-i.html

Solubility

10 mM in DMSO

Smiles

O=C(/C(C)=C/C)C[C@H]([C@@]1(O)C)C2=COC(/C=C/[C@H](C)[C@H](O)C)=CC2=C(C1=O)Cl

Molecular Formula

C22H27ClO5

Molecular Weight

406.90

References & Citations

[1]Yamada T, et al. New class azaphilone produced by a marine fish-derived Chaetomium globosum. The stereochemistry and biological activities. Bioorg Med Chem. 2011;19 (13) :4106-4113.