VMY-2-95
VMY-2-95 is an oral active and blood-brain barrier (BBB) penetrant α4β2 nicotinic acetylcholine receptor desensitizer. VMY-2-95 can be used for study of depression or addiction[1][2].
Product Specifications
CAS Number
1434047-61-6
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vmy-2-95.html
Smiles
C1(OC[C@@H]2CCN2)=CC(C#CC3=CC=CC=C3)=CN=C1
Molecular Formula
C17H16N2O
Molecular Weight
264.32
References & Citations
[1]Kong H, et al. Preclinical studies of the potent and selective nicotinic α4β2 receptor ligand VMY-2-95. Mol Pharm. 2015;12 (2) :393-402. |[2]Yenugonda VM, et al. Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands. J Med Chem. 2013;56 (21) :8404-8421.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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