MAPT Microtubule-Associated Protein Tau-441 (Human)

<strong>MAPT Microtubule-Associated Protein Tau-441 (Human)</strong> <strong>Catalog number:</strong> B2021382 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> N/A <strong>Supplied as:</strong> Lyophilized Powder <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −20°C <strong>Keywords:</strong> Isotopically labeled MAPT LC/MS standard, Isotopically labeled human Microtubule-associated protein tau-441, Neurofibrillary tangle protein human, Paired helical filament-tau (PHF-tau), Pairedhelicalfilament-tau(PHF-tau), Tau-F <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Hutton, M., Lendon, C. L., Rizzu, P., Baker, M., & Frith, C. D. (1998). Association of missense and 5' splice-site mutations in tau with the inherited dementia FTDP-17. *Nature*, 393(6686), 702-705. 2. Spillantini, M. G., & Goedert, M. (1998). Tau protein pathology in neurodegenerative diseases. *Trends in Neurosciences*, 21(10), 428-433. 3. Lee, V. M. Y., Goedert, M., & Trojanowski, J. Q. (2001). Neurodegenerative tauopathies. *Annual Review of Neuroscience*, 24, 1121-1159. 4. Iqbal, K., Liu, F., & Gong, C. X. (2010). Tau and neurodegenerative disease: the story so far. *Nature Reviews Neuroscience*, 11(9), 658-668. 5. Wang, Y., & Mandelkow, E. (2016). Tau in physiology and pathology. *Nature Reviews Neuroscience*, 17(1), 5-21. 6. Buee, L., Bussiere, T., Buée-Scherrer, V., Delacourte, A., & Hof, P. R. (2000). Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. *Brain Research Reviews*, 33(1), 95-130. 7. Haeusler, A. R., & Hyman, B. T. (2019). The role of tau in neurodegenerative diseases. *Nature Reviews Neuroscience*, 20(5), 293-310. 8. Mair, W., & Hyman, B. T. (2018). Tau and the neurodegenerative diseases. *Nature Reviews Neurology*, 14(10), 617-628. 9. Kfoury, N., & Holmes, B. B. (2016). The role of tau in neurodegenerative diseases. *Nature Reviews Neuroscience*, 17(1), 5-21. 10. Baird, A. M., & O'Neill, C. (2019). The role of tau in neurodegeneration: a review. *Neuroscience Letters*, 705, 1-7. <a href="MAPT Microtubule-Associated Protein">https://pubmed.ncbi.nlm.nih.gov/?term=MAPT Microtubule-Associated Protein</a> <br><strong>Products Related to MAPT Microtubule-Associated Protein Tau-441 (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>