Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Luspatercept

Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia[1].

Product Specifications

CAS Number

1373715-00-4

Product Name Alternative

ACE-536; luspatercept–aamt

UNSPSC

12352203

Target

TGF-beta/Smad

Type

Inhibitory Antibodies

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/luspatercept.html

Purity

98.92

Solubility

10 mM in DMSO

Smiles

[Luspatercept]

Molecular Weight

(75.71 kDa)

References & Citations

[1]Suragani RN, et al. Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis. Nat Med. 2014 Apr;20 (4) :408-14.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Phospho-MAPKAPK-2 (Thr334) Monoclonal Antibody
AN300153L-01 20 µL

Recombinant Phospho-MAPKAPK-2 (Thr334) Monoclonal Antibody

Sign In for Pricing
View Details
Recombinant Phospho-MAPKAPK-2 (Thr334) Monoclonal Antibody
AN300153L-02 100 µL

Recombinant Phospho-MAPKAPK-2 (Thr334) Monoclonal Antibody

Sign In for Pricing
View Details
Elab Fluor® 488 Anti-Mouse CD5 Antibody[53-7.3]
E-AB-F1185L-01 50 Tests

Elab Fluor® 488 Anti-Mouse CD5 Antibody[53-7.3]

Sign In for Pricing
View Details
Elab Fluor® 488 Anti-Mouse CD5 Antibody[53-7.3]
E-AB-F1185L-02 100 Tests

Elab Fluor® 488 Anti-Mouse CD5 Antibody[53-7.3]

Sign In for Pricing
View Details
Elab Fluor® 488 Anti-Mouse CD5 Antibody[53-7.3]
E-AB-F1185L-03 2x 100 Tests

Elab Fluor® 488 Anti-Mouse CD5 Antibody[53-7.3]

Sign In for Pricing
View Details
HNRPLL Antibody
8C16119-AAT 50 µg

HNRPLL Antibody

Sign In for Pricing
View Details