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Recombinant Phospho-MAPKAPK-2 (Thr334) Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP24 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Abbreviation

MAPKAPK2

UniProt

P49137

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the residues around (Thr334) of Human Phospho-MAPKAPK-2

Target

MAPKAPK; MAPKAP-K; MAPKAPK2; MAPKAP-K2; MK-2; MK2

Clonality

Monoclonal

Clone

5B4

Conjugation

Unconjugated

Applications

WB

Field of Research

Cardiovascular; Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Observed Molecular Weight

45 kDa;40 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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