L 366763
L 366763 is a potent peptide that acts as a fibrinogen receptor antagonist, preventing collagen-induced platelet aggregation and adhesion. L 366763 inhibits platelet deposition and maintains blood flow in a baboon thrombosis model, significantly prolonging bleeding time. L 366763 has antithrombotic efficacy, whereas recombinant LAPP does not have the same effect[1].
Product Specifications
CAS Number
[154447-41-3]
UNSPSC
12352209
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-366763.html
Smiles
CC(N[C@@H](CS)C(N[C@@H](CC(N)=O)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(N)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C29H48N12O11S2
Molecular Weight
804.90
References & Citations
[1]Recombinant Leech Antiplatelet Protein Prevents Collagen-Mediated Platelet Aggregation but Not Collagen Graft Thrombosis in Baboons
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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