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5-Bromo-3-phenyl salicylic acid

Selected Variant

HY-118819-01

Size: 1 mg

5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM[1].

Product Specifications

CAS Number

99514-99-5

Product Name Alternative

AMD 3100; JM3100; SID791

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-bromo-3-phenyl-salicylic-acid.html

Purity

98.00

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(Br)=CC(C2=CC=CC=C2)=C1O)O

Molecular Formula

C13H9BrO3

Molecular Weight

293.11

Precautions

H302, H315, H319, H335

References & Citations

[1]El-Kabbani O, et al., Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) . J Med Chem. 2009 May 28;52 (10) :3259-64.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

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