5-Bromo-3-phenyl salicylic acid
Product Specifications
Product Name Alternative
AMD 3100; JM3100; SID791
UNSPSC Description
5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM[1].
Target Antigen
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-bromo-3-phenyl-salicylic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Br)=CC(C2=CC=CC=C2)=C1O)O
Molecular Weight
293.11
References & Citations
[1]El-Kabbani O, et al., Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1). J Med Chem. 2009 May 28;52(10):3259-64.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118819/5-Bromo-3-phenyl-salicylic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118819/
Clinical Information
No Development Reported
CAS Number
99514-99-5
Available Sizes
Curated Selection
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