SCH-53870
SCH-53870 is a Ras activation inhibitor that binds to the Ras-GDP complex, keeping the Ras protein in an inactive GDP-bound state and preventing it from switching to an active GTP-bound state. SCH-53870 affects cell signaling and cell proliferation by preventing the activation of Ras protein. SCH-53870 can be used in cancer research[1].
Product Specifications
CAS Number
188480-50-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sch-53870.html
Smiles
O=S(C1=CC=C(NO)C=C1)(NCCOC2=CC=C3C=CC=CC3=C2)=O
Molecular Formula
C18H18N2O4S
Molecular Weight
358.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Colombo, et al. Design and characterization of a new class of inhibitors of ras activation. Annals of the New York Academy of Sciences 1030.1 (2004) : 52-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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