Anisodine (hydrobromide)
Anisodine (Daturamine) hydrobromide is a neuroprotective compound that reduces exacerbated M1, M2, M4, and M5 receptor expression in brain tissues under hypoxia/reoxygenation conditions. Anisodine hydrobromide inhibits calcium ion influx and reactive oxygen species (ROS) levels. Anisodine hydrobromide leads to decreased aspartate levels during hypoxia[1].
Product Specifications
CAS Number
[76822-34-9]
Product Name Alternative
Daturamine (hydrobromide) ; α-Hydroxyscopolamine (hydrobromide)
UNSPSC
12352005
Hazard Statement
H301-H311-H331
Target
Calcium Channel; mAChR; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anisodine-hydrobromide.html
Smiles
CN1[C@@H](C[C@H](OC([C@@](O)(CO)C2=CC=CC=C2)=O)C[C@H]31)[C@H]4[C@@H]3O4.Br
Molecular Formula
C17H22BrNO5
Molecular Weight
400.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
[1]Modulation of muscarinic receptors by anisodine hydrobromide in cerebral ischemia
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
Phase 3
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