Purified Anti-Human CD137 Antibody[BBK-2]

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

CDw; TNFRSF; TNFRSF9;4-1BB; CD137; CDw137; ILA;4-1BB ligand receptor; Induced By Lymphocyte Activation; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNFRSF9;4 1BB;4 1BB ligand receptor;4-1BB Ligand Receptor T Cell; Antigen 4-1BB Homolog; CD 137; CD137 antigen; HLDA VI; homolog of; Homolog of mouse 4 1BB; induced by lymphocyte activation (ILA) ; Interleukin activated receptor homolog of mouse Ly63; Ly63; MGC2172; mouse; OTTHUMP00000044294; Receptor protein 4 1BB; T cell antigen 4 1BB homolog; T cell antigen ILA; TNF receptor superfamily member 9; TNR9; Tumor necrosis factor receptor superfamily member 9