Mevalonolactone

Mevalonolactone is a sesquiterpene lactone that displays calcineurin inhibitory activity towards p-Nitrophenyl phosphate (HY-116022) (IC50 of 134.29 μM) [1].

Product Specifications

CAS Number

[19115-49-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Calcineurin

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mevalonolactone.html

Purity

98.0

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C1C[C@](C)(O)CCO1

Molecular Formula

C6H10O3

Molecular Weight

130.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Xu Z, et al. Pestalotiopisorin B, a new isocoumarin derivative from the mangrove endophytic fungus Pestalotiopsis sp. HHL101. Nat Prod Res. 2020 Apr;34 (7) :1002-1007.