Tridocosahexaenoylglycerol

Tridocosahexaenoylglycerol (TG-DHA) is an orally active dietary supplement that improves autoimmune encephalomyelitis in mice. Tridocosahexaenoylglycerol shows beneficial effects on neurodegenerative diseases and also improves macular function in diabetic retinopathy. Tridocosahexaenoylglycerol can be used for research on neurological diseases, inflammatory immune diseases, and metabolic diseases[1][2][3].

Product Specifications

CAS Number

[124596-98-1]

Product Name Alternative

TG-DHA; Meganol D

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tridocosahexaenoylglycerol.html

Concentration

9.77 mM * 500 μL in Ethanol

Purity

98.7

Solubility

10 mM in DMSO

Smiles

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OC(COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)=O

Molecular Formula

C69H98O6

Molecular Weight

1023.51

Precautions

H225, H319

References & Citations

[1]Mancera P, et al. Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice. Nutrients. 2017 Jun 30;9 (7) :681.|[2]Boyer-Diaz Z, et al. Oxidative Stress in Chronic Liver Disease and Portal Hypertension: Potential of DHA as Nutraceutical. Nutrients. 2020 Aug 28;12 (9) :2627.|[3]Lidich N, et al. Structural characteristics of oil-poor dilutable fish oil omega-3 microemulsions for ophthalmic applications. J Colloid Interface Sci. 2016 Feb 1;463:83-92.