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L3MBTL3, His-tag Recombinant

Human lethal (3) malignant brain tumor-like protein 3 (L3MBTL3), GenBank Accession No. NM_032438, a.a. 229-547 with N-terminal His-tag, MW = 37.6 kDa, expressed in anE. colicell expression system.

Product Specifications

Background

PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.

UniProt

Q96JM7

Tag

N-terminal His-tag

Applications

Useful for the study of Polycomb group (PcG) proteins, protein binding assays, screening inhibitors, and selectivity profiling.

Purity

≥ 88%

Format

Aqueous buffer solution

Shipping Conditions

-80°C

Calculated Molecular Weight

37.6 kDa

Formulation

40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 19 mM imidazole, 0.005% Tween-20, and 20% glycerol.

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