Hydroxyebastine
Hydroxyebastine is an Ebastine (a histamine H1-receptor antagonist) metabolite. Hydroxyebastine is metabolized to Carebastine (HY-121356) by CYP2J2 and CYP3A4[1].
Product Specifications
CAS Number
210686-41-2
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hydroxyebastine.html
Smiles
O=C(CCCN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(C(C)(CO)C)C=C4
Molecular Formula
C32H39NO3
Molecular Weight
485.66
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Liu KH, et al. Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A. Drug Metab Dispos. 2006 Nov;34 (11) :1793-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV782520 1.0 µg DNA
RPS6P18 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
QP9904-ye-50ug 50ug
Recombinant Human Interleukin-26 Protein, His, Yeast-50ug
Sign In for Pricing
View Details bs-3272R-Cy7 100 µL
Phospho-Met (Tyr1234 + Tyr1235) Polyclonal Antibody, Cy7 Conjugated
Sign In for Pricing
View Details 
QP12430-20ug 20ug
Recombinant Human IMMP2L Protein, His, E.coli-20ug
Sign In for Pricing
View Details