LGALS13 Antibody / Galectin 13
It recognizes a 32kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13) . Galectins are a family of soluble β -galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, LGALS13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, LGALS13 exists as a disulfide-linked homodimer. LGALS13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for LGALS13/Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA/sodium azide-free format for coating), Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
Q9UHV8
Host
Mouse
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids 23-134 was used as the immunogen for the LGALS13 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
PP13/1165
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the LGALS13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This LGALS13 antibody is available for research use only.
Storage Conditions
Store the LGALS13 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Titering of the LGALS13 antibody may be required for optimal performance.
Location
Cytoplasmic, cell surface
Image Legend
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