PECAM-1 Antibody / CD31
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood
Host
Mouse
Reactivity
Human
Immunogen
Human recombinant PECAM-1 / CD31 protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
C31.7
Applications
FACS
Purity
Protein G affinity chromatography
Format
CF488 Conjugate
Buffer
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the PECAM-1 antibody at 2-8oC, protected from light.
Limitations
This PECAM-1 antibody is available for research use only.
Storage Conditions
Store the PECAM-1 antibody at 2-8°C, protected from light.
Formulation
500 ul at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the PECAM-1 antibody should be determined by the researcher.
Location
Cell surface, cytoplasmic
Image Legend
FACS testing of human Jurkat cells: Black=cells alone; Green=isotype control; Red=PECAM-1 antibody
Documents
Frequently Asked Questions
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