Recombinant Human/Mouse FGF-8b/FGF8B Protein
Product Specifications
Background
Fibroblast growth factor 8 (FGF-8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen--dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial--mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
Abbreviation
FGF-8b; FGF8B
Synonyms
AIGF; Androgen-induced growth factor; FGF-8B; Fibroblast growth factor 8; HBGF-8; Heparin-binding growth factor 8
UniProt
P55075; P37237
Accession Number
P55075-3/P37237-2
Expression System
E.coli
Tag
None
Sequence
Gln23-Arg215
Applications
Cell culture
Endotoxin
< 0.01 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
50
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
22.5 kDa
Observed Molecular Weight
23 kDa
Species
Human/Mouse
Available Sizes
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