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Keratin 5 Antibody / KRT5

The protein encoded by the KRT5 gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [RefSeq]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:1000-1:5000, Immunohistochemistry (FFPE) : 1:50-1:200

UniProt

P13647

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide specific to human Cytokeratin 5 / KRT5 was used as the immunogen for the Keratin 5 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

FBE-11

Type

Recombinant

Applications

WB, IHC-P

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the Keratin 5 antibody at -20oC.

Limitations

This Keratin 5 antibody is available for research use only.

Storage Conditions

Store the Keratin 5 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Keratin 5 antibody should be determined by the researcher.

Image Legend

Western blot testing of human A431 cell lysate with Keratin 5 antibody. Predicted molecular weight: 58-62 kDa.

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