M6PR Antibody / IGF2R
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
P11717
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human M6PR / IGF2R was used as the immunogen for the M6PR antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
DIC-9
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the M6PR antibody at -20oC.
Limitations
This M6PR antibody is available for research use only.
Storage Conditions
Store the M6PR antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the M6PR antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of human Jurkat cell lysate with M6PR antibody. Predicted molecular weight ~274 kDa.
Documents
Frequently Asked Questions
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