PARP Antibody
The PARP1 gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [RefSeq]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P09874
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human PARP (auto-modification/catalytic segment) was used as the immunogen for the PARP antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
CFD-16
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the PARP antibody at -20oC.
Limitations
This PARP antibody is available for research use only.
Storage Conditions
Store the PARP antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the PARP antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with PARP antibody. Predicted molecular weight ~116 kDa (full length), ~24 kDa (DNA-binding domain) .
Frequently Asked Questions
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