Purified Anti-Mouse CD31 Antibody[MEC13.3], Functional Grade
Product Specifications
Background
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61) . Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Abbreviation
CD31
Synonyms
Adhesion molecule; CD31 antigen; CD31 EndoCAM; CD31/EndoCAM; cluster of differentiation 31; endoCAM; FLJ34100; FLJ58394; GPIIA; GPIIA'; PECA1; Pecam 1; PECAM 1 CD31 EndoCAM; platelet and endothelial cell adhesion molecule 1; Platelet/endothelial cell adhesion molecule 1; CD31; Platelet endothelial cell adhesion molecule; Pecam; Pecam-1; Pecam1; endocam; gpIIa
UniProt
Q08481
Reactivity
Mouse
Immunogen
Recombinant Mouse CD31 protein
Clonality
Monoclonal
Clone
MEC13.3
Conjugation
None (AF/LE)
Applications
FCM; Block
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Host or Source
Rat
Control Catalog Number
E-AB-F098330
Isotype
Rat IgG2a, κ
Available Sizes
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