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Purified Anti-Mouse CD31 Antibody[MEC13.3], Functional Grade

Product Specifications

Background

CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61) . Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

Abbreviation

CD31

Synonyms

Adhesion molecule; CD31 antigen; CD31 EndoCAM; CD31/EndoCAM; cluster of differentiation 31; endoCAM; FLJ34100; FLJ58394; GPIIA; GPIIA'; PECA1; Pecam 1; PECAM 1 CD31 EndoCAM; platelet and endothelial cell adhesion molecule 1; Platelet/endothelial cell adhesion molecule 1; CD31; Platelet endothelial cell adhesion molecule; Pecam; Pecam-1; Pecam1; endocam; gpIIa

UniProt

Q08481

Reactivity

Mouse

Immunogen

Recombinant Mouse CD31 protein

Clonality

Monoclonal

Clone

MEC13.3

Conjugation

None (AF/LE)

Applications

FCM; Block

Purification Method

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Host or Source

Rat

Control Catalog Number

E-AB-F098330

Isotype

Rat IgG2a, κ

Available Sizes

Frequently Asked Questions

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