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KAT7 Antibody

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000

UniProt

O95251

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide specific to human KAT7 / HBO1 / MYST2 was used as the immunogen for the KAT7 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ADAE-11

Type

Recombinant

Applications

WB

Purity

Affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the KAT7 antibody at -20oC.

Limitations

This KAT7 antibody is available for research use only.

Storage Conditions

Store the KAT7 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the KAT7 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) human MCF7, 2) mouse NIH3T3 and 3) rat C6 cell lysate with KAT7 antibody. Predicted molecular weight ~71 kDa.

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