What is the catalog number for EPOR Antibody / EPO Receptor?

The catalog number for EPOR Antibody / EPO Receptor is RQ4025.

What sizes are available for EPOR Antibody / EPO Receptor?

EPOR Antibody / EPO Receptor is available in the following size(s): 100 µg.

Is EPOR Antibody / EPO Receptor in stock?

EPOR Antibody / EPO Receptor is currently made to order / not held in immediate stock. Contact us for lead time.

EPOR Antibody / EPO Receptor

The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

P14753

Host

Rabbit

Reactivity

Rat

Immunogen

A recombinant mouse partial protein corresponding to amino acids D32-E225 was used as the immunogen for the EPOR antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the EPOR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This EPOR antibody is available for research use only.

Storage Conditions

After reconstitution, the EPOR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the EPOR antibody should be determined by the researcher.

Prediction Reactivity

Mouse

Image Legend

Western blot testing of rat lung lysate with EPOR antibody at 0.5ug/ml. Predicted molecular weight ~55 kDa (memebrane bound form), ~29 kDa (soluble form) .