Glabrol
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1].
Product Specifications
CAS Number
59870-65-4
UNSPSC
12352005
Target
Acyltransferase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/glabrol.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C[C@@H](C2=CC=C(O)C(C/C=C(C)\C)=C2)OC3=C(C/C=C(C)\C)C(O)=CC=C13
Molecular Formula
C25H28O4
Molecular Weight
392.49
References & Citations
[1]Choi JH, et al. Glabrol, an acyl-coenzyme A: cholesterol acyltransferase inhibitor from licorice roots. J Ethnopharmacol. 2007 Apr 4;110 (3) :563-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ACAT
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
D5549 96 Tests
G-protein coupled Receptor 35 (GPR35) Mouse ELISA Kit
Sign In for Pricing
View Details 
orb2659432-01 20 µg
Recombinant Human Butyrophilin-like protein 2 (BTNL2), partial
Sign In for Pricing
View Details orb2659432-02 100 µg
Recombinant Human Butyrophilin-like protein 2 (BTNL2), partial
Sign In for Pricing
View Details orb2659432-03 1 mg
Recombinant Human Butyrophilin-like protein 2 (BTNL2), partial
Sign In for Pricing
View Details