P50 Antibody / p105 / NFKB1
Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NFKB1 is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NFKB1 proteins by p105 and generation of p50 by a cotranslational processing.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL
UniProt
P19838
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 1-360) was used as the immunogen for this p50 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, IF
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
The p50 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeat freeze/thaws.
Limitations
This p50 antibody is available for research use only.
Storage Conditions
The p50 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeat freeze/thaws.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Titration of the p50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear, cytoplasmic
Image Legend
Documents
Frequently Asked Questions
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