SOX2 Rabbit Polyclonal Antibody
SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. Sox2, Oct-4 and Nanog co-operate in this network, and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SOX2
Swiss Prot
P48431 Human, P48432 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within N-terminal human SOX2.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
F9, MCF-7, NCCIT
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:20-1:50
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 34 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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