GLUT12 Antibody

GLUT12, also called Solute carrier family 2, facilitated glucose transporter member 12, is a protein that in humans is encoded by the SLC2A12 gene. It belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues. By genomic sequence analysis, this gene is mapped to chromosome 6q23.2. GLUT12 was detected in a perinuclear location in MCF7 cells in the absence of insulin; however, it redistributed to the plasma membrane of MCF7 cells grown continuously in the presence of insulin.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q8TD20

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids 256-272 (SLKDEYQYSFWDLFRSK) were used as the immunogen for this GLUT12 antibody (100% homologous in human, mouse and rat) .

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

Reconstitution

After reconstitution, the GLUT12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This GLUT12 antibody is available for research use only.

Storage Conditions

After reconstitution, the GLUT12 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

The stated application concentrations are suggested starting points. Titration of the GLUT12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.