UVRAG Antibody
UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Product Specifications
UniProt
Q9P2Y5
Host
Rabbit
Immunogen
A portion of amino acids 666-699 from the human protein was used as the immunogen for the UVRAG antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, IHC-P, WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the UVRAG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This UVRAG antibody is available for research use only.
CAS Number
9007-83-4
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