KAP1 Antibody / TRIM28
The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
Q13263
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 178-207 from the human protein was used as the immunogen for the KAP1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KAP1 antibody is available for research use only.
Storage Conditions
Aliquot the KAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Nuclear
Image Legend
Western blot testing of human 1) HeLa and 2) PC-3 cell lysate with KAP1 antibody. Expectd molecular weight: 88~110 kDa depending on sumoylation level.
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