TEC Antibody
TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25
UniProt
P42680
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 175-205 from the human protein was used as the immunogen for the TEC antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TEC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TEC antibody is available for research use only.
Storage Conditions
Aliquot the TEC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of human NCI-H292 cell lysate with TEC antibody. Expected molecular weight: 58-73 kDa (multiple isoforms) .
Documents
Frequently Asked Questions
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