MYBPC3 Mouse Monoclonal Antibody [Clone ID: LBI2E7]

Product Specifications

Background

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

Overview

MYBPC3 mouse monoclonal antibody, clone LBI2E7

Synonyms

CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C

Gene Name

Myosin binding protein C, cardiac

Gene ID

4607

UniProt

Q14896

Conjugation

Unconjugated

Related Pathways

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Field of Research

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Concentration

1 mg/ml

Dilution

ELISA 1:5000-10000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.