Clascoterone-d6
Product Specifications
UNSPSC Description
Clascoterone-d6 (Cortexolone 17 alpha-propionate-d6) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist[1].
Target Antigen
Androgen Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others;Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Smiles
CCC(O[C@@]1(CC[C@]2([C@@]3(CC(C4=C(C(C([2H])(C[C@@]4([C@]3(CC[C@]12C)[H])C)[2H])=O)[2H])[2H])[H])[H])C(C([2H])(O)[2H])=O)=O
Molecular Weight
408.56
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Trifu V, et al. Cortexolone 17伪-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0路05% cream. Br J Dermatol. 2011 Jul;165(1):177-83.|[3]Trifu V, et al. Cortexolone 17α-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0·05% cream. Br J Dermatol. 2011 Jul;165(1):177-83.|[4]Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54(12):881-6.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS642527-01 0.2 mL
LMAN2, CT (LMAN2, C5orf8, Vesicular integral-membrane protein VIP36, Glycoprotein GP36b, Lectin mannose-binding 2, Vesicular integral-membrane protein 36)
Ask
View Details 
MBS642527-02 5x 0.2 mL
LMAN2, CT (LMAN2, C5orf8, Vesicular integral-membrane protein VIP36, Glycoprotein GP36b, Lectin mannose-binding 2, Vesicular integral-membrane protein 36)
Ask
View Details 
MBS1311438 Inquire
Recombinant Arabidopsis thaliana Calmodulin-binding transcription activator 1 (CMTA1) , partial
Ask
View Details 
MBS6391754-01 0.1 mL
RAB43 (Ras-related Protein Rab-43, RAB11B, Ras-related Protein Rab-41, RAB41) (MaxLight 490)
Ask
View Details MBS6391754-02 5x 0.1 mL
RAB43 (Ras-related Protein Rab-43, RAB11B, Ras-related Protein Rab-41, RAB41) (MaxLight 490)
Ask
View Details