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ILK Antibody

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

Product Specifications

UniProt

Q13418

Host

Rabbit

Immunogen

A portion of amino acids 225-253 from the human protein was used as the immunogen for this ILK antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, WB, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ILK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ILK antibody is available for research use only.

CAS Number

9007-83-4

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