GAC0001E5

GAC0001E5 is an LXR inverse agonist. GAC0001E5 has antiproliferative activity and can be used in cancer research[1].

Product Specifications

CAS Number

[927969-67-3]

UNSPSC

12352005

Target

LXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gac0001e5.html

Purity

98.57

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1N=C(NC(C2=CC=CC=C2)=C1)NC3=CC=CC(C(F)(F)F)=C3

Molecular Formula

C17H12F3N3O

Molecular Weight

331.29

References & Citations

[1]Karaboga H, et al. Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity. ACS Chem Biol. 2020 Nov 20;15 (11) :2916-2928.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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