GAC0001E5
Product Specifications
UNSPSC Description
GAC0001E5 is an LXR inverse agonist. GAC0001E5 has antiproliferative activity and can be used in cancer research[1].
Target Antigen
LXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gac0001e5.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1N=C(NC(C2=CC=CC=C2)=C1)NC3=CC=CC(C(F)(F)F)=C3
Molecular Weight
331.29
References & Citations
[1]Karaboga H, et al. Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity. ACS Chem Biol. 2020 Nov 20;15(11):2916-2928.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160039/GAC0001E5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160039/
Clinical Information
No Development Reported
CAS Number
927969-67-3
Available Sizes
Curated Selection
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