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HER2 Antibody

ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.

Product Specifications

CAS Number

9007-83-4

UniProt

P04626

Host

Rabbit

Immunogen

This HER2 antibody was produced from rabbits immunized with human recombinant ErbB2 protein.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, FACS, IF, ELISA

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the HER2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HER2 antibody is available for research use only.

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