STAT1 Antibody
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P42224
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 717-745 from the human protein was used as the immunogen for this STAT1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the STAT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This STAT1 antibody is available for research use only.
Storage Conditions
Aliquot the STAT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the STAT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
STAT1 antibody western blot analysis in (1) HeLa and (2) Jurkat lysate. Predicted molecular weight: ~91/84kDa (alpha/beta) .
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