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WNT6 Antibody

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q9Y6F9

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 173-201 from the human protein was used as the immunogen for this WNT6 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the WNT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This WNT6 antibody is available for research use only.

Storage Conditions

Aliquot the WNT6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the WNT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

WNT6 antibody western blot analysis in HepG2 lysate

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